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Start your gut health challenge: https://zoe.com/products-ghc

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Six weeks. Three lives. Will it work?

Most of us think we know what healthy eating looks like. But the reality is, the system makes it impossible – confusing labels, misleading marketing, and diets that leave us tired, low energy, and unsure what to eat.

We invited Sarah, Rob, and Lucy to take on a challenge: could they transform their health using nothing but science-led nutrition? No calorie counting, no restrictive lists – just eating for their unique biology, guided by Professor Tim Spector and ZOE’s world-leading scientists.

At the start, they were held back by brain fog, poor sleep, and constant tiredness. Could a six-week nutritional reset really move the needle?

From the truth behind supermarket labels to the power of a personalized gut score, go behind the scenes of ‘The Gut Health Challenge’ and discover what happens when you finally start eating for your gut.

This is not about extreme diets or perfect eating. It’s a brave, science-led look at what may truly make a difference, and the life-changing effects when you take back control of your health.

49 Comments

  1. Hi Thanks Zoe I am doing the plan as far as I can because you are not available in Australian. Please come down under

  2. Fantastic video and Super Fun watching it!! I L💛VE your Daily30+ . Just received 4 more bags yesterday, and just got done finishing my meal with your sprinkles 😃 Whenever I see my cheery yellow ZOE tin I smile ~ I feel deeply grateful for everything I’ve learned from Tim Spector and your team ✨

  3. who thought it would be a good idea to play music while people are talking very annoying and no other Zoe video is like it

  4. Interesting of course – but to much an advert for Zoe, Zoe, Zoe, Zoe, Zoe, Zoe …

  5. the approach is amazing, I've been doing Zoe for over 3y now, lost stones in weight and changed my life, can't thank them enough for that. The downside is the Zoe1 app wasn't without issue but was a mine of useful logging and recipe suggestions and was a great support tool for the science, the relaunched 2.0 app is dire and heading down an AI slop approach to things and I doubt very much I'd have got as much out of Zoe starting now as I have done from years on the first version of the app. Their software has always felt like you are paying to use an alpha/beta version and it's only got worse with 2.0 which lacks many of the features previously available. Brilliant life changing science, poor software.

  6. If you can follow one rule of not using MRP (milk and milk products refined food and packed food) in your life you can get multiple benefits like balanced weight, high energy and more life.

    Many of my patients are getting the benefits.
    🤗🙌🙏

  7. Really helpful video thank you. It’s a shame that Zoe no longer completes the blood test as part of their screening process as this was pivotal especially to the gentleman to have that knowledge with increased drive to change

  8. Very coy about triglyceride score. Would have been useful to get actual initial and final scores. Why were they not given?

  9. is there any gut test that actually tells us the species present? From all the ZOE talks, I had hoped one would get a clear insight in Status q, and could nerd out on the microbiome. Does the result of the test really only show this calculated health score?

  10. Something that should be looked at more closely by Zoe is hormone replacement therapy during perimenopause and menopause. Dr Louise Newsom would be a great guest on the show.

  11. So many Aussies following Zoe and apparently unable to access your services. I would have thought Commonwealth countries would get priority. ❤

  12. The self-reported stuff is a bit of a nonsense. People on a short term study know to overstate how bad things are at the start, and how good they are at the end. I wouldn't take the slightest notice of any of those "results", other than the measurable (hours of sleep, for instance).

  13. I have low LDL and high triglicerides even though I feel that I have a good varied diet. Is it because I have an ileostomy. If so, is there any way I can reduce my triglceride level.

  14. Big Zoe fan in Italy, I follow the advice without the testing or app. Made a huge difference to my diet, health and how I feel. Regular listener to the Zoe podcast too. Please spread the availability to Europe.

  15. When you mention to the average person… mixed nuts, mixed beans and lentils, watch them turn their nose up at it and say, I'm not eating that, if they even know what it is. You have to give them recipes, flavour and something to look forward to.

  16. I did ZOE for one year . I found it very interesting but hard at times . I feel amazingly now and I look at all food in a different way .
    I would love to have been selected to do this with the team !

  17. OMG, where can I get such a great black curly wig? Or is it perhaps a shower cap 🤔???

  18. I'm delighted that you seem to help a lot of people, but I'm not one of them. I have watched many of your videos, and you consistently seem to take the easy path, studiously avoiding giving any advice to those who suffer from the Inflammatory Bowel Diseases: Crohn's and Ulcerative Colitis. Surely you could at least acknowledge us, and make clear where following what you are saying would be counter productive for us? Your approach undermines my confidence in what you say. Perhaps I have just missed all the episodes in which you acknowledge these chronic and life changing illnesses, and the people who suffer from them. If so, I apologise. I'd be grateful if you would identify the ones in which you give us advice too. I am prepared to respect you and your work if this is the case but unfortunately, all I can see is that you run a business to financially support your research and make your names by focusing on the easy stuff.

  19. It would be lovely to have some recipes featured on the channel. And perhaps some day on an ideal Zoe Diet. With cook a long videos to help being concepts to life

  20. Sorry. This video is an annoying cacophony of noise and is not nice to listen to. Leave out the annoying music and silly sounds if you want people to understand what you are saying.

  21. It's really just common sense…eat a large variety of plants…cook your food most of the time…don't beat yourself up if you do eat junk..just pick yourself up and begin again..it's a mindset about what foods we choose to eat. Eat more fiber; eat more fruits and vegetables.

  22. Great documentary, thank you. I see a lot of people in the comments asking about Zoe in Australia and New Zealand. I am in NZ. I would recommend buying – or getting from the library – Tim's book of recipes The Food For Life Cookbook and Hugh Fearnley-Whittingstall's How To Eat 30 Plants A Week which was written in collaboration with Tim. There's also Food For Life by Tim if you want the science back-up. Listen to the Zoe podcast as well and you will be well on your way to accessing all the benefits in this doco.

  23. As someone really interested in gut health, my 3 key takeaways: real data proves diet can transform health fast, small sustainable changes work better than strict diets, and the gut–brain connection is more powerful than most people realize.

  24. I really hope that Sarah will consider taking HRT. A healthy diet and exercise will definitely help but at the end of the day properly prescribed HRT is vital too! Especially as women live so much longer without our hormones now and suffer the poor health associated with that. Louise Newson podcast and the Louise Newson Balance app. Are great ways to educate oneself about our hormones.

  25. It is mind blowing to me how people can eat less than 10 plants a week. I already had 7 at lunch. You can count coffee, herbs and spices as well.

    Also a bit disappointed in Zoe. When I first learned about Zoe I really thought it was about helping people but now with the paid membership and the horrible 30+ supplement it seems about making money. If you really care about helping people you would teach them how to eat healthy without a silly supplement.

  26. Wow, Zoe. You have no fewer than three participants, two of whom are from the same household. Is that the best you could get? Speaking as a scientist, this is truly pathetic.

  27. At 47:46 Sarah says the woman’s CRP score decreased by 13%. What is the coefficient of variation for this type of assay? I bet is just about or even a bit higher than 13%. Meaning that 13% decrease may well be within the variability of the assay. Unless Sarah averaged multiple readouts before and after, respectively..

  28. What a great documentary . I follow all your podcasts and have become extremely interested in the microbiome . I would love to your ZOE group but unfortuneatly I live in the Netherlands . Are you , in the near future , thinking of going European ! Thank you all for your wonderful work .

  29. I can not eat breakfast and work, makes me feel sick and lethargic. My first meal is anywhere between 14h and 17h depending on how busy the day is. Om the rare occasions that I am hungry and have breakfast then I tend to eat all day..picking

  30. I'm glad you included an ND person as well. There's a link with autistic and ADHD and gut issues so it's important to show that. I did the Zoe program a few years ago and learnt a lot about food pairing etc.

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